probiotics

Probiotics and NAFLD

This review assessed the efficacy of probiotics, prebiotics or synbiotics in the management of non-alcoholic fatty liver disease (NAFLD). A total of 1309 patients with NAFLD from 25 studies (11 probiotic, 9 prebiotic and 7 synbiotic) were included in the meta-analysis. All three treatments combined significantly reduced BMI (-0.37 kg/m2), hepatic alanine aminotransferase (−6.9 U/L), aspartate …

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Probiotics and atopy prevention

Probiotics significantly reduced the risk of atopic sensitisation by 29% when administered prenatally to the pregnant mother and postnatally to infant (RR 0.71; 95% CI, 0.57 to 0.89) and the risk of food sensitization (RR 0.77; 95% CI, 0.61 to 0.98)1. The meta-analysis of 17 studies with 4755 children showed that probiotic supplementation during pregnancy …

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Probiotics for the airways

Probiotics showed improvement of the clinical symptoms and quality of life in allergic rhinitis patients. The results from the studies investigating the potential of probiotic supplementation in the treatment of patients with asthma are promising. Probiotics can modulate nasal epithelial barrier via the expression and regulation of tight junctions and adherence junctions resulting in the …

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Probiotics and respiratory allergies

Respiratory allergies caused by house dust mites are one of the most common triggers of allergic rhinitis and asthma. This review summarises the current evidence for the use of probiotics in the prevention and treatment of respiratory allergic conditions. Probiotics appear to improve the symptom scores and quality of life in patients with allergic rhinitis …

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Gut microbiota in nutrition and health

Human gut microbiota plays a key role in disease, nutrition and health. Antibiotics, medications and specific food ingredients influence the composition and diversity of the gut microbiota. Targeting the gut microbiome with probiotics, prebiotics or dietary fibre is beneficial for human health. The analysis of 22 systematic reviews (313 trials, 46 826 participants) showed that …

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Upper respiratory symptoms in athletes

Upper tract respiratory symptoms such as sneezing, coughing, sore throat, runny and blocked nose are common among athletes during heavy training and competition. This review focuses on the aetiology of upper respiratory symptoms, mucosal immunity, the role of the gut and airway microbiomes and the use of probiotics and prebiotics to maintain athlete health.   …

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Probiotics and acidosis in healthy children

A review of five randomised controlled trials from 2005 to 2017 with 544 healthy infants (one day to 12 months of age) showed that D-lactic acid producing probiotic bacteria and fermented infant formulas did not cause D-lactic acidosis in healthy children. The only reported cases of paediatric D-lactic acidosis were in children with short bowel …

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