Gastrointestinal Tract

A relationship between the gut microbiota and atherosclerosis

This study investigated the role of gut microbiota in atherosclerosis, a major cause of heart attack and stroke. 316 patients attending vascular prevention clinics in Canada were divided into three distinct phenotypes; (i) 98 patients with much less carotid plaque than predicted by traditional risk factors (Protected), (ii) 138 patients with plaque levels as predicted …

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Probiotics for the prevention of Clostridium difficile infection

The aim of this recent study was to find out whether the probiotic supplementation alongside antibiotic treatment will reduce the incidence of Clostridium difficile infection in adults and children. Individual data of 6851 participants from 18 published randomised controlled trials were included in the statistical analysis. 72.2% of the studies were conducted in adult hospitalised …

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Probiotics in the management of lower gastrointestinal symptoms

A systematic review of 70 studies investigating the use of probiotics in the management of lower gastrointestinal symptoms (IBS, antibiotic-associated diarrhoea, diarrhoea associated with Helicobacter pylori eradication therapy and other conditions) was performed, evidence was graded and recommendations for the physicians provided. Specific probiotics are beneficial in (i) reduction of total symptoms and abdominal pain …

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Probiotics for recurrent abdominal pain

The effect of dietary interventions for recurrent abdominal pain in 1453 children aged between 4 and 18 years was assessed in the Cochrane systematic review of 19 randomised controlled trials. Thirteen studies (1017 children) investigated the effect of probiotics compared to placebo, four studies (299 children) were trials of fibre-based interventions, one study (34 children) …

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